IL-1 inhibition in systemic juvenile idiopathic arthritis
Systemic juvenile idiopathic arthritis Rope Reins (sJIA) is the form of childhood arthritis whose treatment is most challenging.The demonstration of the prominent involvement of interleukin (IL)-1 in disease pathogenesis has provided the rationale for the treatment with biologic medications that antagonize this cytokine.The three IL-1 blockers that